Using Deep UV Raman Spectroscopy to Identify Biomarkers for Dementia

Wide Blue 28 June 2025

Dementia affects millions worldwide, significantly impairing memory, cognition, and daily functioning. It is the leading cause of death in England. As the population ages, experts anticipate an increase in cases. This makes early and accurate diagnosis crucial for better patient outcomes and healthcare planning. Current diagnostic methods rely on cognitive assessments, imaging, and invasive procedures, such as cerebrospinal fluid analysis. These are costly and not always definitive.

Identifying reliable biomarkers in blood samples could revolutionise dementia diagnosis, providing a faster, less invasive alternative. Deep UV Raman spectroscopy offers a promising solution by detecting subtle biochemical changes in serum samples. Unlike conventional Raman methods, deep UV Raman minimises fluorescence interference, enhancing sensitivity and specificity in biomarker detection.

This article explores the potential of deep UV Raman technology in dementia research, detailing its advantages, challenges, and recent findings. With further validation, this innovative approach could pave the way for earlier, more precise diagnoses, ultimately improving patient care and treatment strategies

Read the full article at IS-Instruments: Using Deep UV Raman Spectroscopy to Identify Biomarkers for Dementia